Prevacid (lansoprazole) is a proton pump inhibitor (PPI) prescribed for the treatment and management of conditions related to excess stomach acid. By targeting the acid-producing pumps in the stomach lining, it provides sustained relief from symptoms such as heartburn, regurgitation, and discomfort associated with gastroesophageal reflux disease (GERD). Available in delayed-release capsules and orally disintegrating tablets, it offers flexible dosing options under medical supervision. Clinical studies support its efficacy in healing erosive esophagitis and maintaining symptom-free periods.

Features

• Active ingredient: Lansoprazole 15 mg or 30 mg
• Form: Delayed-release capsules and orally disintegrating tablets
• Mechanism: Proton pump inhibitor (PPI)
• Prescription-only medication
• Delayed-release formulation protects the drug from stomach acid
• Suitable for short-term and maintenance therapy

Benefits

• Provides long-lasting reduction of stomach acid production
• Promotes healing of acid-damaged esophageal tissue
• Reduces frequency and severity of heartburn and GERD symptoms
• Helps prevent recurrence of erosive esophagitis
• May be used in combination with antibiotics for H. pylori eradication
• Improves overall quality of life by enabling comfortable eating and resting

Common use

Prevacid is commonly prescribed for the treatment of gastroesophageal reflux disease (GERD), including symptomatic relief and healing of erosive esophagitis. It is also used in the management of pathological hypersecretory conditions such as Zollinger-Ellison syndrome. Additionally, it is indicated for short-term treatment of active duodenal ulcers and as part of combination therapy for Helicobacter pylori infection eradication to reduce the risk of ulcer recurrence.

Dosage and direction

The typical adult dosage for GERD is 15‒30 mg once daily for up to 8 weeks. For maintenance healing of erosive esophagitis, 15 mg daily is recommended. H. pylori eradication regimens usually involve 30 mg of Prevacid twice daily alongside antibiotics for 10‒14 days. Prevacid should be taken before a meal, preferably in the morning. Capsules must be swallowed whole; do not crush or chew. Orally disintegrating tablets should be placed on the tongue without water.

Precautions

Patients should inform their healthcare provider of any history of liver disease, osteoporosis, or low magnesium levels. Long-term use may increase the risk of bone fractures, particularly in older adults. Avoid use beyond the prescribed duration without reevaluation. Not intended for immediate relief of heartburn symptoms. Use during pregnancy only if clearly needed; caution is advised while breastfeeding.

Contraindications

Prevacid is contraindicated in patients with known hypersensitivity to lansoprazole or any component of the formulation. Concomitant use with rilpivirine-containing products is contraindicated due to the potential for reduced antiviral efficacy. Should not be used in patients taking drugs whose absorption is pH-dependent, such as certain antifungals or HIV medications, without medical supervision.

Possible side effect

Common side effects may include headache, diarrhea, abdominal pain, and nausea. Less frequently, dizziness, rash, or constipation may occur. Long-term use has been associated with hypomagnesemia, vitamin B12 deficiency, and an increased risk of Clostridium difficile-associated diarrhea. Severe side effects, though rare, may include kidney inflammation, lupus erythematosus, or fundic gland polyps.

Drug interaction

Prevacid may interact with drugs that require gastric acid for absorption, such as ketoconazole, iron salts, and digoxin. It can alter the metabolism of warfarin, theophylline, and tacrolimus, potentially requiring dose adjustments. Concurrent use with methotrexate may increase methotrexate toxicity. Consult a healthcare provider before combining with other prescription or over-the-counter medications.

Missed dose

If a dose is missed, take it as soon as remembered unless it is nearly time for the next dose. Do not double the dose to make up for a missed one. Resume the regular dosing schedule with the next dose. Consistent daily use is important for optimal therapeutic effect.

Overdose

There is limited experience with human overdose. Expected manifestations may reflect an exaggeration of the pharmacologic effects, such as hypersecretion or gastrointestinal symptoms. Management is supportive and symptomatic; there is no specific antidote. Hemodialysis is not effective due to high protein binding. In case of suspected overdose, seek immediate medical attention or contact a poison control center.

Storage

Store at room temperature (20‒25°C or 68‒77°F), away from moisture, light, and heat. Keep the bottle tightly closed and out of reach of children. Do not use beyond the expiration date printed on the packaging. Do not remove desiccant from the bottle.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Do not disregard professional medical advice or delay in seeking it because of something you have read here.

Reviews

Clinical trials and post-marketing surveillance indicate high patient satisfaction with Prevacid for symptom control in GERD and ulcer healing. Many users report significant improvement in quality of life, though individual responses may vary. Some note the convenience of the orally disintegrating formulation for those who have difficulty swallowing capsules. Long-term users are advised to periodically reassess treatment necessity with their healthcare provider.