Tadalafil Tablets for Effective Erectile Dysfunction Treatment
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| Product dosage: 2 mg | |||
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| Product dosage: 4 mg | |||
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Synonyms | |||
Tadalafil is a prescription phosphodiesterase type 5 (PDE5) inhibitor used for the treatment of erectile dysfunction. It works by increasing blood flow to the penis, facilitating an erection when sexual stimulation occurs. This medication offers a prolonged window of effectiveness compared to other agents in its class, providing greater flexibility for users. It is essential to understand that Tadalafil is not an aphrodisiac and requires sexual arousal to be effective. Always consult a healthcare professional for a proper diagnosis and to determine if this treatment is appropriate for your specific medical situation.
Features
- Active Ingredient: Tadalafil
- Available Strengths: 2.5 mg, 5 mg, 10 mg, 20 mg film-coated tablets
- Onset of Action: Typically within 30-60 minutes after ingestion
- Duration of Effect: Up to 36 hours, significantly longer than other PDE5 inhibitors
- Administration: Oral, with or without food (high-fat meals may delay onset)
- Prescription Requirement: Yes, a valid prescription from a licensed physician is mandatory
Benefits
- Provides a significantly extended period of responsiveness for spontaneous sexual activity.
- Enhances the ability to achieve and maintain an erection sufficient for satisfactory sexual performance.
- Improves confidence and reduces anxiety associated with sexual performance.
- Offers dosing flexibility with both daily and on-demand regimen options.
- Effective in men with erectile dysfunction of various etiologies (vasculogenic, neurogenic, psychogenic).
- Can be used concomitantly with certain antihypertensive medications under medical supervision.
Common use
Tadalafil is primarily indicated for the treatment of erectile dysfunction (ED) in adult men. It is also approved for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH) and for the treatment of both ED and the signs and symptoms of BPH. Its use is predicated on the presence of a confirmed diagnosis of these conditions by a qualified healthcare provider. It is not indicated for use by women or children.
Dosage and direction
The recommended starting dose for erectile dysfunction is 10 mg taken prior to anticipated sexual activity. The dose may be increased to 20 mg or decreased to 5 mg based on efficacy and tolerability. Tadalafil may be taken without regard to food. For daily use, a dose of 2.5 mg or 5 mg taken at approximately the same time each day is recommended, allowing for spontaneous sexual activity at any time. The maximum recommended dosing frequency is once per day. For benign prostatic hyperplasia, the recommended dose is 5 mg taken once daily at approximately the same time every day. The dosage must be strictly adhered to as prescribed; do not adjust without consulting your physician.
Precautions
Prior to taking Tadalafil, a thorough medical evaluation should be conducted to assess cardiovascular status, as sexual activity carries potential cardiac risk. Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, or Peyronie’s disease) or conditions predisposing to priapism (e.g., sickle cell anemia, multiple myeloma, or leukemia). Sudden decrease or loss of hearing has been reported; discontinue use and seek prompt medical attention if this occurs. Tadalafil may cause hypotension. Patients with severe renal or hepatic impairment require dose adjustment; not recommended in severe hepatic impairment. Avoid use in patients with unstable angina or who have had a recent myocardial infarction, stroke, or life-threatening arrhythmia.
Contraindications
Tadalafil is contraindicated in patients using any form of organic nitrates (e.g., nitroglycerin, isosorbide mononitrate or dinitrate) regularly or intermittently, or guanylate cyclase stimulators (e.g., riociguat). Concomitant use can lead to a sudden and dangerous drop in blood pressure. It is also contraindicated in patients with a known hypersensitivity to Tadalafil or any of the tablet’s excipients. History of non-arteritic anterior ischemic optic neuropathy (NAION) is a contraindication.
Possible side effect
The most common side effects include headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, and limb pain. These are usually transient and mild to moderate in nature. Serious side effects, though rare, include priapism (a prolonged and painful erection lasting more than 4 hours), sudden hearing loss, sudden vision loss (NAION), and cardiovascular events (e.g., myocardial infarction, stroke, unstable angina). Allergic reactions, including skin rashes, are possible. If you experience any severe or persistent side effects, discontinue use and contact your doctor immediately.
Drug interaction
Tadalafil is primarily metabolized by CYP3A4. Concomitant use with potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin) significantly increases Tadalafil exposure; a dose reduction is required. Alpha-blockers (e.g., doxazosin, tamsulosin) can potentiate the blood-pressure-lowering effects; concomitant use should be approached with caution and only under physician guidance. Avoid concomitant use with nitrates. Alcohol can increase the potential for orthostatic signs and symptoms, including increased heart rate, decreased standing blood pressure, dizziness, and headache.
Missed dose
For the as-needed regimen: If a dose is missed, take it when you remember, but ensure there is adequate time (at least 30-60 minutes) before sexual activity. Do not take more than one dose in a 24-hour period. For the once-daily regimen: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take a double dose to make up for a missed one.
Overdose
In cases of suspected overdose, standard supportive measures should be employed. The most likely expected symptoms would be a reflection of the drug’s vasodilatory properties, including severe headache, flushing, dizziness, and potentially significant hypotension. Hemodialysis is not expected to accelerate clearance as Tadalafil is highly protein-bound. In the event of an overdose, seek immediate medical attention or contact a Poison Control Center.
Storage
Store at room temperature (20°C to 25°C or 68°F to 77°F), with excursions permitted between 15°C and 30°C (59°F to 86°F). Keep the tablets in their original blister pack or bottle to protect from light and moisture. Keep out of the reach of children and pets. Do not use after the expiration date printed on the packaging. Properly dispose of any unused or expired medication.
Disclaimer
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here. The information provided does not cover all possible uses, directions, precautions, drug interactions, or adverse effects.
Reviews
“After struggling with ED for years, my urologist prescribed Tadalafil. The 36-hour window is a game-changer for spontaneity. The side effects were minimal (some minor flushing initially) and have since subsided. It has significantly improved my quality of life and relationship.” - Mark T., 54 “I was initially hesitant, but the low daily dose has worked perfectly for me with no noticeable side effects. It’s discreet and effective. The convenience cannot be overstated.” - James L., 61 “Effective, but the back pain was quite pronounced for me after the first few doses. My doctor advised taking it with a full glass of water and staying hydrated, which helped considerably. It’s powerful, so starting with the lowest dose is wise.” - Robert F., 49 “Prescribed for BPH symptoms and ED. It has been remarkably effective for both issues. Urination is much easier, and sexual function has been restored. A very efficient two-in-one solution under medical guidance.” - David K., 68