Prilox Cream is a clinically formulated topical treatment designed to provide fast and effective relief from the pain, itching, and swelling associated with hemorrhoids. Combining the potent local anesthetic lidocaine with the vasoconstrictor phenylephrine, it offers targeted symptomatic control, reducing inflammation and discomfort within minutes of application. Its optimized formulation ensures minimal systemic absorption, making it a preferred choice for both acute episodes and recurrent symptoms. Suitable for adults seeking non-invasive management, Prilox Cream supports comfort and daily functioning without the need for oral analgesics or procedural interventions.

Features

• Contains lidocaine hydrochloride 5% w/w and phenylephrine hydrochloride 0.5% w/w
• Water-miscible base for easy application and absorption
• Steroid-free formulation to avoid skin thinning or systemic effects
• Available in 30g tubes with hygienic applicator
• Rapid onset of action (within 3–5 minutes)
• Provides up to 3–4 hours of symptomatic relief per application

Benefits

• Delivers immediate numbing effect to alleviate pain and tenderness
• Reduces swelling and inflammation through localized vasoconstriction
• Minimizes itching and irritation, preventing scratching and secondary infection
• Supports uninterrupted daily activities and rest
• Non-greasy, odorless, and non-staining for discreet use
• Avoids gastrointestinal side effects associated with oral analgesics

Common use

Prilox Cream is indicated for the temporary relief of discomfort associated with external hemorrhoids, including pain, itching, burning, and irritation. It is also used for symptomatic relief in cases of minor anorectal inflammation, post-episiotomy discomfort, and irritation following anorectal surgery. Patients often apply it during acute flare-ups or as needed for persistent symptoms, though prolonged use should be under medical supervision.

Dosage and direction

Apply externally to the affected area up to 4 times daily, or as directed by a physician. Wash hands before and after application. Clean and dry the anal area thoroughly. Apply a thin layer of cream; do not rub vigorously. Use the applicator for hygienic and precise application. Avoid contact with eyes, mucous membranes, or broken skin. Treatment should not exceed 7 days without medical advice.

Precautions

• For external use only
• Do not use on infected areas unless directed by a healthcare provider
• Discontinue if rash, increased irritation, or hypersensitivity occurs
• Avoid tight clothing to prevent further irritation
• Not recommended for children under 12 years of age
• Consult a physician if symptoms persist beyond 7 days or worsen
• Use with caution in patients with cardiovascular disease, hypertension, thyroid disorder, or diabetes

Contraindications

• Hypersensitivity to lidocaine, phenylephrine, or any component of the formulation
• History of methemoglobinemia
• Application to large areas of broken or inflamed skin
• Use in patients taking monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants
• Severe or bleeding hemorrhoids without medical evaluation

Possible side effects

• Mild and transient burning, stinging, or redness at the application site
• Skin dryness or peeling
• Allergic contact dermatitis (rare)
• Systemic effects such as dizziness, tachycardia, or hypertension with excessive use
• Blanching of the skin due to vasoconstriction

Drug interaction

• May interact with antiarrhythmic drugs (e.g., tocainide, mexiletine)
• Potential additive effects with other sympathomimetic agents
• Caution with beta-blockers or digitalis due to cardiovascular effects
• MAOIs and tricyclic antidepressants may enhance pressor effects

Missed dose

Apply as soon as remembered if within a reasonable time frame. Do not double the dose to make up for a missed application. Resume the regular dosing schedule.

Overdose

Excessive application may lead to systemic absorption, resulting in symptoms such as CNS depression (drowsiness, dizziness), cardiovascular effects (hypertension, bradycardia), or methemoglobinemia (cyanosis, shortness of breath). In case of suspected overdose, discontinue use, remove cream, and seek medical attention immediately.

Storage

Store at room temperature (15–30°C). Keep away from direct sunlight and moisture. Do not freeze. Keep out of reach of children and pets. Discard any unused product after the treatment course.

Disclaimer

This information is for educational purposes only and does not replace professional medical advice. Always consult a healthcare provider for diagnosis and personalized treatment recommendations. Use only as directed. The manufacturer is not liable for misuse or adverse outcomes.

Reviews

“As a gastroenterologist, I frequently recommend Prilox Cream for patients with acute hemorrhoidal symptoms. Its rapid action and favorable safety profile make it a reliable option for outpatient management.” – Dr. A. Reynolds, MD
“Provided noticeable relief within minutes. The applicator makes it easy to use hygienically.” – Verified User
“Effective for reducing swelling post-hemorrhoidectomy. Prefer it over other topical agents due to its non-greasy texture.” – Clinical Nurse
“I’ve used it for occasional flare-ups for years. It doesn’t irritate my sensitive skin like some other products.” – Long-term User