Gyne-Lotrimin is a leading over-the-counter antifungal medication specifically formulated to treat vulvovaginal candidiasis. Its active ingredient, clotrimazole, directly targets the cell membranes of Candida albicans and other susceptible fungi, disrupting their integrity and leading to fungal cell death. This topical cream provides symptomatic relief from itching, burning, and discharge while effectively eradicating the underlying infection. Trusted by healthcare professionals and patients alike, it offers a convenient, targeted solution for uncomplicated vaginal yeast infections.

Features

• Contains 2% clotrimazole as the active antifungal ingredient
• Available in 1 oz (28.4 g) tube with measured-dose applicator
• Water-miscible cream base for easy application and absorption
• pH-balanced formulation compatible with vaginal environment
• No prescription required for OTC purchase
• Manufactured under strict pharmaceutical quality standards

Benefits

• Provides rapid relief from itching, burning, and irritation within days of initiation
• Effectively eliminates the causative fungal organisms to resolve infection
• Convenient once-daily dosing regimen for patient compliance
• Minimal systemic absorption reduces risk of widespread side effects
• Can be used during daytime activities without significant leakage or discomfort
• Prevents recurrence when used as directed for the full treatment course

Common use

Gyne-Lotrimin is indicated for the local treatment of vulvovaginal candidiasis (vaginal yeast infections). It is appropriate for patients experiencing characteristic symptoms including vaginal itching, burning, soreness, and abnormal discharge. The medication is specifically designed for uncomplicated infections in non-pregnant, immunocompetent individuals. Healthcare providers may recommend it as first-line therapy for patients with confirmed or suspected candidiasis who meet appropriate use criteria.

Dosage and direction

Apply one applicatorful (approximately 5 grams) intravaginally once daily at bedtime for 3 consecutive days for the standard course. For severe or recurrent infections, a 7-day treatment course may be recommended. Wash hands before and after application. Lie on back with knees bent for proper insertion. Gently insert the applicator into the vagina and press the plunger to release the medication. Clean the applicator with mild soap and water after each use. Complete the full course of treatment even if symptoms improve earlier.

Precautions

For external use only in the vaginal area. Avoid contact with eyes. Do not use if allergic to clotrimazole or any other ingredients. Do not use with diaphragms or condoms as the mineral oil base may damage latex. Sexual intercourse should be avoided during treatment as the cream may weaken condoms and diaphragms. Consult a healthcare provider if symptoms persist after 7 days or worsen at any time. Not for use in children under 12 years without medical supervision.

Contraindications

Hypersensitivity to clotrimazole, other imidazoles, or any component of the formulation. Not for systemic or oral use. Should not be used by patients with known immunodeficiency disorders without medical supervision. Contraindicated in patients with fever, abdominal pain, or foul-smelling discharge as these may indicate more serious conditions requiring different treatment. Not recommended during the first trimester of pregnancy unless specifically advised by a healthcare provider.

Possible side effects

Mild burning, itching, or irritation upon application (usually transient). Skin rash or redness in the application area. Vaginal discomfort including cramping or pain. Headache may occur in some patients. Urinary frequency or discomfort. These effects are typically mild and resolve with continued use. Discontinue and consult a healthcare provider if severe reactions occur including blistering, swelling, or intense burning that does not subside.

Drug interaction

No significant drug interactions have been reported with topical vaginal clotrimazole due to minimal systemic absorption. However, concurrent use with other vaginal products may alter efficacy or increase irritation. Avoid using with other antifungal agents unless directed by a healthcare provider. The mineral oil base may interact with latex contraceptives (condoms, diaphragms), reducing their effectiveness. Inform your healthcare provider about all medications you are taking, including prescription, OTC, and herbal products.

Missed dose

Apply the missed dose as soon as remembered, unless it is almost time for the next scheduled dose. Do not double the dose to make up for a missed application. Continue with the regular dosing schedule. If multiple doses are missed, the treatment course may need to be extended—consult product information or a healthcare provider for guidance.

Overdose

Topical overdose is unlikely due to limited systemic absorption. Excessive application may cause increased local irritation, burning, or itching. If the product is ingested orally, seek immediate medical attention or contact a poison control center. Symptomatic and supportive care should be provided if necessary. There is no specific antidote for clotrimazole overdose.

Storage

Store at room temperature (15-30°C or 59-86°F). Keep tube tightly closed when not in use. Do not freeze. Keep out of direct sunlight and excessive heat. Keep out of reach of children and pets. Do not use after expiration date printed on packaging. Discard any medication that appears discolored or has changed consistency.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new medication or treatment. The product should be used only as directed on the label or as prescribed by a healthcare provider. Individual results may vary. The manufacturer is not liable for any incorrect usage or adverse outcomes resulting from improper application.

Reviews

Clinical studies demonstrate 80-90% efficacy in treating uncomplicated vaginal yeast infections when used as directed. Patients report significant symptom improvement within 2-3 days of initiation. Healthcare providers frequently recommend Gyne-Lotrimin as first-line OTC treatment due to its proven efficacy and favorable safety profile. Many users appreciate the convenience of the short treatment course and minimal side effects compared to oral alternatives.