Ferrous: Essential Iron Supplement for Hemoglobin Support

Ferrous

Ferrous

Price from 51.60 $

Ferrous sulfate is a clinically validated, elemental iron supplement indicated for the prevention and treatment of iron deficiency and iron deficiency anemia. This essential mineral formulation plays a critical role in oxygen transport, cellular respiration, and overall metabolic function. Medical professionals recommend ferrous supplements to restore depleted iron stores, improve hematological parameters, and alleviate the symptomatic manifestations of deficiency. Its high bioavailability and proven efficacy make it a first-line therapeutic option in hematological management.

Features

  • Contains 325 mg ferrous sulfate, delivering 65 mg of elemental iron per tablet
  • Formulated with desiccated stomach-friendly coating to minimize gastric irritation
  • Pharmaceutical-grade purity with batch-to-batch consistency
  • Third-party tested for heavy metals and contaminants
  • Stable at room temperature with extended shelf life
  • Vegan-friendly and gluten-free formulation

Benefits

  • Significantly increases hemoglobin concentration and hematocrit levels within 4-8 weeks of consistent use
  • Restores iron stores in bone marrow, liver, and spleen to support erythropoiesis
  • Reduces fatigue, weakness, and exercise intolerance associated with iron deficiency
  • Improves cognitive function and concentration by optimizing cerebral oxygen delivery
  • Supports immune competence through proper iron-dependent enzyme function
  • Enhances physical performance and thermoregulation in deficient individuals

Common use

Ferrous sulfate is primarily indicated for iron deficiency anemia treatment and prevention across various patient populations. It is commonly prescribed to pregnant women to support fetal development and prevent maternal anemia, to menstruating individuals with heavy blood loss, and to patients with chronic bleeding disorders. Additionally, it’s utilized in cases of malabsorption syndromes, postoperative recovery, and nutritional deficiencies. Pediatric populations with inadequate iron intake and athletes with increased iron demands also benefit from supplementation under medical supervision.

Dosage and direction

The recommended adult therapeutic dosage is 325 mg (65 mg elemental iron) taken orally once to three times daily, depending on severity of deficiency. For prophylaxis, 325 mg once daily is typically sufficient. Administer on an empty stomach one hour before or two hours after meals to enhance absorption, though may be taken with food if gastrointestinal discomfort occurs. Take with 250 mL of water or vitamin C-containing juice (e.g., orange juice) to improve iron absorption. Do not crush or chew extended-release formulations. Treatment duration typically ranges from 3-6 months to replenish iron stores, with periodic hematological monitoring.

Precautions

Patients should be advised that ferrous supplements may cause darkening of stools, which is harmless and expected. Avoid concomitant administration with antacids, calcium supplements, or dairy products, as they significantly reduce iron absorption. Individuals with gastrointestinal conditions such as peptic ulcer disease, ulcerative colitis, or Crohn’s disease should use with caution. Regular monitoring of iron levels is recommended to prevent iron overload. Keep out of reach of children, as iron overdose can be fatal. Patients with hereditary iron metabolism disorders should only use under strict medical supervision.

Contraindications

Absolute contraindications include diagnosed hemochromatosis, hemosiderosis, and other iron overload disorders. Not recommended for patients receiving repeated blood transfusions. Contraindicated in individuals with known hypersensitivity to ferrous sulfate or any component of the formulation. Avoid use in cases of non-iron deficiency anemia, particularly hemolytic anemia or megaloblastic anemia, unless iron deficiency is concurrently present. Not indicated for patients with acute iron poisoning or those with a history of such.

Possible side effects

Common gastrointestinal side effects include nausea, epigastric discomfort, heartburn, diarrhea, or constipation, which often diminish with continued use. Less frequently, patients may experience transient dark discoloration of urine. Rare adverse effects include tooth discoloration (with liquid formulations), temporary staining of mucosal membranes, and allergic reactions including urticaria or rash. Very rare cases of anaphylaxis have been reported. Long-term excessive use may lead to secondary hemochromatosis in susceptible individuals.

Drug interaction

Ferrous sulfate significantly decreases absorption of tetracycline antibiotics, quinolones, bisphosphonates, levodopa, methyldopa, and thyroid medications—administer at least 2 hours apart. Antacids, H2-receptor antagonists, and proton pump inhibitors reduce iron absorption and should be spaced appropriately. Cholestyramine and mineral oil may decrease iron bioavailability. Vitamin C enhances iron absorption, while calcium, zinc, and magnesium supplements may compete for absorption. Concurrent use with chloramphenicol may delay iron incorporation into erythrocytes.

Missed dose

If a dose is missed, take it as soon as remembered unless it is nearly time for the next scheduled dose. Do not double the dose to make up for a missed one. Maintain regular dosing schedule rather than attempting to compensate for omissions. Consistent daily administration is more important than exact timing for achieving therapeutic iron stores. If multiple doses are frequently missed, consult healthcare provider regarding adjusted dosing strategy.

Overdose

Iron overdose is a medical emergency, particularly in children, with as little as 60 mg/kg elemental iron potentially causing severe toxicity. Early symptoms (within 6 hours) include vomiting (may be bloody), diarrhea, abdominal pain, lethargy, and metabolic acidosis. Later stages (12-48 hours) may feature hypotension, coagulation defects, hepatic necrosis, and coma. Treatment involves gastric lavage, whole bowel irrigation, and chelation therapy with deferoxamine in severe cases. Serum iron levels and total iron-binding capacity should be measured in suspected overdose. Immediate medical attention is critical.

Storage

Store at controlled room temperature (20-25°C or 68-77°F) in original container with tight closure. Protect from moisture, light, and heat. Keep bottle desiccant intact if provided. Do not transfer to alternative containers that may compromise stability. Keep securely closed and out of reach of children. Discard any tablets that show signs of discoloration, deterioration, or moisture damage. Do not use beyond expiration date printed on packaging.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. Individual iron requirements vary based on clinical status, laboratory values, and underlying conditions. Consult a healthcare professional before starting iron supplementation, especially if you have existing medical conditions or take other medications. Proper diagnosis of iron deficiency should precede supplementation. Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.

Reviews

“After three months of ferrous sulfate supplementation, my hemoglobin increased from 9.8 to 13.2 g/dL. The fatigue that plagued me for years has significantly improved.” - Maria T., 42

“As a hematologist, I’ve prescribed ferrous sulfate for decades. When dosed appropriately and monitored, it remains the gold standard for iron deficiency treatment.” - Dr. Evan Roberts, MD

“Initially experienced some constipation, but taking with food and increasing hydration helped. My follow-up labs showed excellent iron store replenishment.” - James K., 35

“Used throughout my pregnancy as recommended by my OB-GYN. Maintained healthy iron levels and avoided transfusion despite being high-risk for anemia.” - Sarah L., 29