Avana (avanafil) is a prescription phosphodiesterase type 5 (PDE5) inhibitor specifically formulated for the treatment of erectile dysfunction. As a next-generation medication in its class, it offers a rapid onset of action, high selectivity, and a favorable side effect profile compared to earlier agents. Clinically proven to improve erectile function, Avana enables reliable response and greater spontaneity, supporting both physiological and psychological aspects of sexual health under appropriate medical supervision.

Features

• Active ingredient: Avanafil 50 mg, 100 mg, or 200 mg per tablet
• Rapid onset: Can work in as little as 15 minutes after ingestion
• High selectivity for PDE5 enzyme, reducing off-target effects
• Duration of efficacy: Up to 6 hours
• Oral administration; no injection or topical application required
• Manufactured under strict pharmaceutical quality controls

Benefits

• Enables reliable and sustainable erectile improvement sufficient for successful intercourse
• Allows for greater spontaneity due to fast onset of action
• Reduces planning anxiety and performance-related stress
• Supports confidence and relationship satisfaction through restored sexual function
• Minimizes common side effects associated with less selective PDE5 inhibitors
• Provides a predictable and controllable treatment window

Common use

Avana is indicated for the management of erectile dysfunction (ED) in adult males. It is used to facilitate achieving and maintaining an erection when accompanied by sexual stimulation. It is not indicated for use in women, children, or adolescents. Avana does not protect against sexually transmitted infections, nor does it increase sexual desire.

Dosage and direction

The recommended starting dose of Avana is 100 mg taken orally approximately 15–30 minutes before anticipated sexual activity. Based on efficacy and tolerability, the dose may be increased to 200 mg or decreased to 50 mg. Do not take more than one tablet within a 24-hour period. Avana may be taken with or without food; however, high-fat meals may delay onset of action. Do not crush, split, or chew the tablet.

Precautions

• Use only under the supervision of a healthcare provider; do not share medication
• Not intended for continuous daily use
• Avoid excessive alcohol consumption, as it may increase risk of side effects and decrease efficacy
• Use caution in patients with anatomical deformation of the penis or conditions that may predispose to priapism
• Cardiovascular status should be assessed before prescribing; sexual activity poses potential cardiac risk
• Not recommended for use with other ED treatments or recreational drugs

Contraindications

• Concomitant use of organic nitrates in any form
• History of hypersensitivity to avanafil or any component of the formulation
• Patients with severe hepatic impairment
• Concurrent use with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
• Unstable angina, recent myocardial infarction, or life-threatening arrhythmia

Possible side effects

Common side effects may include headache, flushing, nasal congestion, back pain, and dyspepsia. Less frequently reported effects include dizziness, visual disturbances, and palpitations. Priapism (a prolonged and painful erection lasting more than 4 hours) is a rare but serious side effect requiring immediate medical attention to prevent permanent damage.

Drug interaction

Avana is primarily metabolized by CYP3A4. Concomitant use with CYP3A4 inhibitors may increase avanafil exposure. Avoid use with alpha-blockers due to risk of hypotension. Do not use with other PDE5 inhibitors, nitrates, guanylate cyclase stimulators, or recreational drugs containing nitrites (“poppers”). Inform your physician of all medications, including over-the-counter and herbal products.

Missed dose

Avana is taken on an as-needed basis. There is no dosing schedule; therefore, missed dose protocols do not apply. Do not take a double dose to make up for a missed opportunity.

Overdose

In case of suspected overdose, seek immediate medical attention. Symptoms may include severe headache, hypotension, syncope, or prolonged erection. Supportive measures should be administered; hemodialysis is not expected to enhance elimination.

Storage

Store at room temperature (20–25°C), in the original container, away from light, moisture, and heat. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.

Disclaimer

This information is intended for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before starting or changing any medication. Do not disregard or delay seeking medical advice based on content provided here.

Reviews

“After trying earlier PDE5 inhibitors, I switched to Avana under my doctor’s guidance. The speed of action and reduced side effects have significantly improved my experience and confidence.” — Verified User

“As a urologist, I find Avana to be a valuable option for patients seeking a fast-acting agent with a cleaner side effect profile. Its selectivity is a notable advantage in clinical practice.” — Dr. R. Evans, MD

“I appreciate that I don’t have to plan hours ahead. With Avana, I feel more in control and spontaneous, which has helped reduce performance anxiety.” — Verified User