Aleve, with its active ingredient naproxen sodium, is a nonsteroidal anti-inflammatory drug (NSAID) designed to provide long-lasting relief from minor aches and pains. It is clinically formulated to reduce inflammation at the source, offering up to 12 hours of continuous symptom control with a single dose. This makes it a preferred choice for individuals managing persistent discomfort associated with conditions such as arthritis, muscle strains, menstrual cramps, and headaches. Its extended-release mechanism allows for sustained therapeutic effect, reducing the frequency of dosing and improving patient compliance. Healthcare professionals often recommend Aleve for its efficacy and well-established safety profile when used as directed.

Features

• Active ingredient: Naproxen sodium (220 mg per tablet/caplet)
• Formulation: Coated tablets, liquid gels, and easy-to-swallow caplets
• Duration of action: Provides relief for up to 12 hours per dose
• Anti-inflammatory properties: Reduces prostaglandin production to alleviate swelling and pain
• Non-narcotic and non-habit forming
• Available over-the-counter in various package sizes

Benefits

• Delivers powerful, targeted relief for a wide range of inflammatory and non-inflammatory pain types.
• Reduces the need for frequent redosing, allowing for uninterrupted daily activities and improved sleep.
• Minimizes inflammation at the tissue level, addressing the root cause of pain rather than merely masking symptoms.
• Supports mobility and functional improvement in chronic conditions like osteoarthritis.
• Offers a non-opioid alternative for pain management, reducing risks associated with narcotic analgesics.
• Trusted by healthcare providers for its consistent performance and evidence-based results.

Common use

Aleve is commonly used for the temporary relief of minor aches and pains due to:

• Arthritis (osteoarthritis and rheumatoid arthritis)
• Musculoskeletal injuries (sprains, strains, backache)
• Menstrual cramps
• Headaches, including tension-type and migraine
• Toothaches
• Tendinitis and bursitis
• The common cold and associated body aches

Dosage and direction

For adults and children 12 years and older:

• Take 1 tablet/caplet every 8 to 12 hours while symptoms persist.
• Do not exceed 2 tablets/caplets in any 8- to 12-hour period.
• Do not exceed 3 tablets/caplets in 24 hours.
• Take with a full glass of water; may be taken with food or milk to minimize stomach upset.
• Swallow whole; do not crush, chew, or break the tablet.
• Use the smallest effective dose for the shortest duration needed to control symptoms.

Precautions

• Do not use if you have had an allergic reaction (e.g., asthma, urticaria) to aspirin or other NSAIDs.
• Consult a doctor before use if you have a history of stomach ulcers or bleeding disorders.
• Not recommended for use immediately before or after heart surgery.
• May increase risk of heart attack, stroke, and gastrointestinal bleeding, especially with prolonged use.
• Use with caution in patients with hypertension, heart failure, or kidney impairment.
• Avoid alcohol consumption during treatment, as it may increase risk of stomach bleeding.
• Discontinue use and consult a physician if pain persists for more than 10 days or fever for more than 3 days.

Contraindications

Aleve should not be used by individuals with:

• Known hypersensitivity to naproxen, aspirin, or other NSAIDs
• History of asthma, rhinitis, or nasal polyps associated with NSAID use
• Active peptic ulcer disease or gastrointestinal bleeding
• Severe heart failure
• Third trimester of pregnancy
• Severe renal impairment (CrCl <30 mL/min)
• Coronary artery bypass graft (CABG) surgery

Possible side effects

Common side effects may include:

• Heartburn, nausea, abdominal pain
• Dizziness, headache
• Mild fluid retention
• Constipation or diarrhea

Serious side effects (seek medical attention if experienced):

• Signs of gastrointestinal bleeding (black/tarry stools, vomiting blood)
• Chest pain, shortness of breath, weakness on one side of the body (signs of cardiovascular events)
• Skin rash, blistering, or itching
• Swelling of the face, lips, or tongue
• Unexplained weight gain or edema
• Changes in urine output or yellowing of the skin/eyes

Drug interaction

Aleve may interact with:

• Anticoagulants (e.g., warfarin): increased risk of bleeding
• Other NSAIDs or corticosteroids: increased risk of GI toxicity
• ACE inhibitors, ARBs, or diuretics: reduced antihypertensive effect and potential renal impairment
• Lithium: increased lithium levels and toxicity risk
• Methotrexate: increased methotrexate toxicity
• SSRIs/SNRIs: increased risk of bleeding
• Cyclosporine: increased nephrotoxicity

Missed dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to make up for a missed one.

Overdose

Symptoms of overdose may include:

• Drowsiness, heartburn, nausea, vomiting
• Agitation, confusion, incoordination
• Gastrointestinal bleeding
• Acute renal failure, respiratory depression

In case of suspected overdose, seek immediate medical attention or contact a poison control center. Do not induce vomiting unless directed by a healthcare professional.

Storage

• Store at room temperature (20–25°C or 68–77°F).
• Keep in the original container, tightly closed.
• Protect from moisture and light.
• Keep out of reach of children and pets.
• Do not use if the packaging is torn or broken.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. Use only as directed on the label or as prescribed by your healthcare provider.

Reviews

Aleve is consistently rated highly by consumers and healthcare professionals for its effectiveness in managing pain and inflammation. Many users report significant improvement in quality of life, especially those with chronic arthritis. Common praises include its long-lasting effect, reduced pill burden, and reliability. Some note mild gastrointestinal discomfort, which is often mitigated by taking with food. Overall, it remains a top recommendation in the NSAID category for balanced efficacy and tolerability.