Nurofen is a leading over-the-counter analgesic and anti-inflammatory medication, with its active ingredient ibuprofen providing effective relief from a wide range of acute pain conditions. As a non-steroidal anti-inflammatory drug (NSAID), it works by inhibiting the production of prostaglandins, chemicals in the body that cause pain, fever, and inflammation. This dual-action mechanism makes it a versatile choice for both common ailments and more specific inflammatory pain. Trusted by healthcare professionals and consumers globally, it represents a cornerstone in symptomatic management.

Features

• Active Ingredient: Ibuprofen (typically 200mg per tablet in standard OTC formulations)
• Formulation: Film-coated tablets for easier swallowing
• Mechanism of Action: Cyclooxygenase (COX-1 and COX-2) enzyme inhibition
• Onset of Action: Typically within 30 minutes when taken on an empty stomach
• Duration of Effect: Up to 8 hours of sustained relief per dose
• Non-Prescription Status: Available over-the-counter in most regions
• Multiple Formulations: Also available as capsules, liquid capsules, and suspension for pediatric use

Benefits

• Provides potent relief from mild to moderate pain, including headaches, dental pain, and muscular aches
• Effectively reduces inflammation at the site of injury or condition, addressing the root cause of many pain types
• Offers antipyretic properties to reduce fever in adults and children
• Rapid onset of action allows for quick symptomatic control
• Suitable for short-term management of menstrual pain and associated inflammation
• Does not contain codeine or other opiate derivatives, minimizing certain dependency risks

Common use

Nurofen is commonly used for the temporary relief of minor aches and pains associated with conditions such as the common cold, headache, toothache, muscular aches, backache, and minor arthritis pain. It is also indicated for the reduction of fever. For inflammatory conditions such as sprains, strains, or tendinitis, it helps reduce swelling and improve mobility. Many users find it effective for managing primary dysmenorrhea (menstrual cramps) due to its anti-prostaglandin effects.

Dosage and direction

For adults and children over 12 years, the usual dose is 1-2 tablets (200-400mg ibuprofen) every 4-6 hours as needed. Do not exceed 6 tablets (1200mg) in 24 hours unless directed by a physician. For maximum absorption, take with a full glass of water. It may be taken with food or milk to minimize gastric upset, though this can slightly delay onset. For pediatric suspension, dosage is weight-based—always use the measuring device provided and consult packaging for age-specific guidelines. Treatment should be limited to the shortest duration necessary to control symptoms.

Precautions

Do not use for more than 10 days for pain or 3 days for fever unless directed by a doctor. Avoid alcohol consumption during use, as it may increase risk of stomach bleeding. Use with caution in patients with a history of gastrointestinal disorders such as ulcers or bleeding. Patients with hypertension, cardiac conditions, renal impairment, or dehydration should consult a healthcare provider before use. Not recommended during the third trimester of pregnancy. Prolonged use may increase the risk of heart attack or stroke.

Contraindications

Nurofen is contraindicated in patients with known hypersensitivity to ibuprofen, aspirin, or other NSAIDs. Do not use in individuals with a history of asthma, urticaria, or allergic-type reactions after taking aspirin or NSAIDs. Contraindicated in patients with severe hepatic impairment, active peptic ulcer disease, or gastrointestinal bleeding. Should not be used peri-operatively for coronary artery bypass graft (CABG) surgery. Not for use in children under 6 months of age unless specifically formulated and recommended for that age group.

Possible side effect

Common side effects may include nausea, epigastric pain, heartburn, dizziness, or headache. Less frequently, rash, tinnitus, fluid retention, or mild gastrointestinal bleeding may occur. Rare but serious side effects include gastrointestinal ulceration or perforation, severe hypersensitivity reactions (e.g., anaphylaxis), hepatotoxicity, renal impairment, and cardiovascular thrombotic events. Patients should discontinue use and seek medical attention if they experience signs of allergic reaction, chest pain, shortness of breath, weakness on one side of the body, slurred speech, or black, tarry stools.

Drug interaction

Ibuprofen may interact with anticoagulants like warfarin, increasing bleeding risk. Concurrent use with other NSAIDs or corticosteroids may elevate the risk of GI adverse effects. It may reduce the effectiveness of antihypertensive drugs including ACE inhibitors and diuretics. Interaction with lithium can lead to increased lithium levels. Methotrexate toxicity risk may be increased. Aspirin taken concurrently may diminish cardioprotective effects. Always inform your healthcare provider of all medications, including supplements and herbal products, being taken.

Missed dose

As Nurofen is taken on an as-needed basis for symptomatic relief, there is no fixed dosing schedule. If you are using it regularly under medical direction and miss a dose, take it as soon as you remember. If it is nearly time for the next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.

Overdose

In case of overdose, symptoms may include nausea, vomiting, epigastric pain, drowsiness, blurred vision, tinnitus, or more severely, metabolic acidosis, coma, or acute renal failure. Seek immediate medical attention or contact a poison control center. Do not induce vomiting unless directed by medical personnel. Treatment is supportive and may include gastric lavage, activated charcoal, and correction of electrolyte imbalances.

Storage

Store at room temperature (15-30°C) in a dry place, protected from light and moisture. Keep the bottle tightly closed and out of reach of children. Do not use if the packaging is torn or shows signs of tampering. Do not transfer tablets to alternative containers. Discard any unused suspension after 6 months of opening.

Disclaimer

This information is for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before starting any new medication, especially if you have pre-existing conditions or are taking other drugs. Do not disregard professional medical advice or delay seeking it because of something you have read here. Use only as directed on the label or as prescribed by your physician.

Reviews

“As a physiotherapist, I often recommend Nurofen for acute musculoskeletal injuries. Its anti-inflammatory action provides measurable benefits in recovery time.” — Dr. Emily R., Healthcare Professional

“I’ve used Nurofen for migraines for years. It’s fast-acting and reliable without making me drowsy, which is essential for my job.” — Mark T., Regular User

“The pediatric suspension was a lifesaver when my child had a high fever. Easy to administer and effective within the hour.” — Sarah L., Parent

“I appreciate that it doesn’t contain caffeine or other stimulants. It targets the pain directly without additional side effects.” — James K., Frequent User