Elimite (permethrin) 5% cream is a topical prescription medication specifically formulated for the eradication of scabies infestations and their eggs. As a synthetic pyrethroid, it offers a potent, targeted approach to parasiticide therapy, providing relief from the intense itching and skin irritation caused by Sarcoptes scabiei mites. Its mechanism of action disrupts the sodium channel current in the parasite’s nervous system, leading to paralysis and death, while its low mammalian toxicity profile makes it a cornerstone of dermatological treatment protocols. Clinically proven and widely recommended by healthcare professionals, Elimite represents a first-line defense in restoring skin health and eliminating parasitic infection.

Features

• Contains 5% permethrin as the active pharmaceutical ingredient
• Formulated in a water-washable, fragrance-free cream base
• Exhibits both insecticidal and ovicidal (egg-killing) properties
• Prescription-only medication, ensuring supervised use
• Single-application treatment in most cases (with potential repeat dose)
• Topical administration minimizes systemic absorption

Benefits

• Provides complete eradication of scabies mites and their eggs, breaking the life cycle
• Rapidly alleviates the intense pruritus (itching) associated with scabies infestation
• Minimizes risk of secondary bacterial infections from scratching
• Helps prevent transmission of scabies to close contacts and family members
• Offers a non-greasy, easy-to-apply formulation that is well-tolerated on skin
• Supported by extensive clinical evidence and decades of therapeutic use

Common use

Elimite cream is primarily indicated for the treatment of scabies, a contagious skin infestation caused by the mite Sarcoptes scabiei var. hominis. It is appropriate for use in both adults and children aged 2 months and older. The medication may also be used off-label for the treatment of head lice (pediculosis capitis) in certain clinical scenarios, though other permethrin formulations are typically preferred for this indication. Diagnosis should be confirmed by a healthcare provider before initiation of treatment to ensure appropriate therapeutic management.

Dosage and direction

Apply a sufficient quantity of Elimite cream to cover the entire body from the neck down, including all skin surfaces such as between fingers and toes, in the axillary areas, and in the groin and gluteal folds. Pay particular attention to areas where mites commonly burrow. The cream should be left on for 8-14 hours before being thoroughly washed off with soap and water. Most patients require only a single application, though a second treatment may be recommended 7-14 days later if new burrows or live mites appear. For infants and young children, also apply to the scalp, temples, and forehead, avoiding the eye and mouth areas.

Precautions

• For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes.
• Do not apply to acutely inflamed or broken skin unless directed by a physician.
• If accidental eye contact occurs, flush immediately with copious amounts of water.
• May cause temporary itching, burning, or stinging immediately after application.
• All clothing, bedding, and towels used by the infected person should be washed in hot water and dried on high heat or dry-cleaned to prevent reinfestation.
• Close contacts and household members may require simultaneous treatment to prevent cross-infection.

Contraindications

Elimite is contraindicated in patients with known hypersensitivity to permethrin, any other synthetic pyrethroids, pyrethrins, chrysanthemums, or any component of the formulation. It should not be used in patients who have demonstrated allergic reactions to previous permethrin applications. There are no absolute contraindications based on age for patients over 2 months, though caution is advised in elderly patients with compromised skin barrier function.

Possible side effects

Most side effects are mild and transient. Common reactions include:

• Pruritus (itching), which may temporarily worsen after application
• Mild burning or stinging sensation
• Erythema (redness), edema (swelling), or rash at application site
• Numbness or tingling sensation

Less frequently reported effects include:

• Skin rash
• Headache
• Dizziness
• Abdominal pain
• Diarrhea

Severe allergic reactions are rare but may include difficulty breathing, swelling of the face, lips, tongue, or throat, and severe dizziness. Seek immediate medical attention if these occur.

Drug interaction

No significant drug interactions have been formally established with topical permethrin due to minimal systemic absorption. However, caution is advised when using Elimite concurrently with other topical medications, particularly those that may enhance skin permeability or cause skin irritation. Avoid simultaneous application of other lotions, creams, or ointments unless directed by a healthcare provider. Patients using corticosteroids topically should consult their physician before application, as steroid use may mask signs of infection or infestation.

Missed dose

As Elimite is typically administered as a single application, the concept of a “missed dose” does not apply in the conventional sense. If the application is washed off prematurely (before 8 hours), reapply the medication as soon as possible and maintain contact for the full recommended duration. If discovered near the end of the treatment period (after 12+ hours), simply wash off as directed. Do not apply additional cream unless specifically instructed by a healthcare provider, as overapplication may increase the risk of adverse effects.

Overdose

Topical overdose is unlikely to cause serious systemic effects due to minimal absorption. However, excessive application may lead to intensified local reactions including severe skin irritation, burning, or erythema. If the cream is accidentally ingested, seek medical attention immediately. Symptoms of oral ingestion may include nausea, vomiting, abdominal pain, headache, dizziness, and in severe cases, nervous system effects such as tremors or incoordination. Treatment is supportive and symptomatic.

Storage

Store at room temperature between 20°C to 25°C (68°F to 77°F). Do not freeze. Keep the tube tightly closed when not in use. Protect from excessive heat and direct sunlight. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging. Properly discard any unused medication after treatment completion.

Disclaimer

This information is provided for educational purposes only and does not constitute medical advice. Elimite is a prescription medication that should be used only under the supervision of a qualified healthcare professional. Always follow your physician’s instructions regarding dosage, application, and treatment duration. Individual results may vary, and not all patients will experience the same outcomes. Consult your healthcare provider for proper diagnosis and treatment recommendations specific to your medical condition.

Reviews

Clinical studies have demonstrated Elimite’s efficacy, with cure rates typically exceeding 90% after a single application in compliant patients. Dermatologists frequently regard permethrin 5% cream as the gold standard for scabies treatment due to its favorable efficacy-to-safety ratio. Patient reviews often highlight significant relief from itching within days of treatment, though some report temporary worsening of symptoms immediately after application. The convenience of single-application therapy is frequently cited as a significant advantage over older treatments requiring multiple applications. Healthcare providers appreciate its established safety profile in diverse patient populations, including young children and pregnant women (when medically necessary).