Antivert (meclizine HCl) is a trusted antihistamine medication specifically formulated to prevent and treat symptoms associated with vertigo, dizziness, and motion sickness. By targeting the vestibular system, it helps reduce nausea, vomiting, and the sensation of spinning, enabling patients to regain balance and functional comfort. Clinically proven and widely prescribed, Antivert offers a non-sedating option for those seeking reliable management of vestibular disorders, making daily activities and travel manageable again.

Features

• Active ingredient: Meclizine hydrochloride 12.5 mg or 25 mg
• Formulation: Oral tablets
• Pharmacologic class: Antihistamine (H1-receptor antagonist) with antiemetic and antivertigo properties
• Onset of action: Typically within 1 hour
• Duration of effect: Up to 24 hours
• Prescription status: Available by prescription and in some over-the-counter formulations
• Manufacturer: Pfizer and various generic manufacturers

Benefits

• Reduces the frequency and severity of vertigo episodes, helping restore equilibrium.
• Prevents and alleviates nausea and vomiting associated with motion sickness.
• Minimizes dizziness, allowing for improved mobility and daily function.
• Long-lasting effect supports all-day or all-night symptom control with a single dose.
• Non-sedating at recommended doses for most individuals, supporting alertness.
• Well-established safety profile with decades of clinical use and patient trust.

Common use

Antivert is commonly prescribed for the management of vertigo related to diseases affecting the vestibular system, such as Ménière’s disease, labyrinthitis, and vestibular neuronitis. It is also widely used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness during travel by car, plane, or boat. Off-label, it may be used to manage nausea in pregnancy or other conditions under medical supervision, though this is not its primary indication.

Dosage and direction

For vertigo: The typical adult dosage is 25–100 mg daily, divided into doses as directed by a healthcare provider, often starting with 25 mg taken at bedtime. For motion sickness: The recommended dose is 25–50 mg taken one hour before travel, which may be repeated every 24 hours for the duration of the journey. Tablets should be swallowed whole with water, with or without food. Dosage adjustments may be necessary for elderly patients or those with hepatic impairment. Always follow the specific instructions provided by your prescriber.

Precautions

Patients should use caution when operating machinery or driving until they know how Antivert affects them, as drowsiness may occur. Alcohol and other central nervous system depressants should be avoided, as they can enhance sedative effects. Use in elderly patients may require dose reduction due to increased sensitivity. Those with glaucoma, prostate enlargement, or respiratory conditions should consult a healthcare provider before use. Pregnancy and breastfeeding require medical advice prior to initiation.

Contraindications

Antivert is contraindicated in individuals with a known hypersensitivity to meclizine or other antihistamines of the same class. It should not be used in patients with narrow-angle glaucoma or urinary retention due to its anticholinergic effects. Use in neonates or infants is not recommended. Avoid in patients with severe liver impairment unless under strict medical supervision.

Possible side effect

Common side effects may include drowsiness, dry mouth, blurred vision, and headache. Less frequently, patients may experience fatigue, nervousness, vomiting, or constipation. Rare but serious side effects can include palpitations, rash, difficulty urinating, or signs of an allergic reaction such as swelling or difficulty breathing. Most side effects are mild and transient, but persistent or severe symptoms should be reported to a healthcare professional.

Drug interaction

Antivert may interact with other CNS depressants, including alcohol, benzodiazepines, opioids, and tranquilizers, potentially increasing sedation. Anticholinergic drugs, such as atropine or certain antidepressants, may enhance side effects like dry mouth or blurred vision. Concomitant use with monoamine oxidase inhibitors (MAOIs) is not recommended. Always inform your healthcare provider of all medications, supplements, and herbal products you are taking.

Missed dose

If a dose is missed, take it as soon as you remember unless it is almost time for the next scheduled dose. Do not double the dose to make up for a missed one. For motion sickness use, take the dose as soon as possible if remembered before or during travel; if remembered after travel has ended, it may not be necessary.

Overdose

Symptoms of overdose may include extreme drowsiness, seizures, hallucinations, or coma. In case of suspected overdose, seek emergency medical attention or contact a poison control center immediately. Treatment is typically supportive and may include monitoring vital signs and administering activated charcoal if ingestion was recent.

Storage

Store Antivert at room temperature (15–30°C or 59–86°F) in a tightly closed container, away from light, moisture, and heat. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication. Do not disregard professional medical advice or delay in seeking it because of something you have read here.

Reviews

Clinical studies and patient reports consistently affirm the efficacy of Antivert in managing symptoms of vertigo and motion sickness. Many users describe significant improvement in quality of life, with reduced dizziness and nausea. Some note mild drowsiness, which often diminishes with continued use. Overall, it remains a well-regarded option within the medical community for vestibular symptom control.